Спорт
Аланин
Зависит от условий. Есть данные: выносливость на нагрузках 0.5-10 мин.
Суть
Мета-анализ в пуле: по β-аланину, а это другое вещество, не α-аланин; по самому α-аланину данных нет.
Что говорят исследования
Форма важна
Данных по α-аланину нет, покупать нечего. Если интересует выносливость, в пуле есть только препарат β-аланина..
Мифы
«Бета-аланин: это аланин»: разные вещества: β-аланин идёт в мышечный карнозин, α-аланин не изучался ни в одной работе пула.
«Данные есть»: они по β-аланину, общий эффект 0.18 при 1461 участнике.
Осторожно
В пуле смешаны три темы: β-аланин для выносливости, антидепрессанты и питание женщин-спортсменок; сам аланин не изучался.
С лекарствами
Из еды
В abstract'ах пула пищевые источники не обсуждаются: мета-анализ по β-аланину касался перорального приёма препарата.
Источники
Обзоры исследований: 44 в Europe PMC, самые цитируемые
Alanine aminotransferase, gamma-glutamyltransferase, and incident diabetes: the British Women's Heart and Health Study and meta-analysis. 2009 · цитирований: 302
β-alanine supplementation to improve exercise capacity and performance: a systematic review and meta-analysis. 2017 · цитирований: 198
Effects of β-alanine supplementation on exercise performance: a meta-analysis. 2012 · цитирований: 191
Durability of HBeAg seroconversion following antiviral therapy for chronic hepatitis B: relation to type of therapy and pretreatment serum hepatitis B virus DNA and alanine aminotransferase. 2003 · цитирований: 126
Gamma glutamyltransferase, alanine aminotransferase and risk of cancer: systematic review and meta-analysis. 2015 · цитирований: 87
Systematic review with meta-analysis: the proportion of chronic hepatitis B patients with normal alanine transaminase ≤ 40 IU/L and significant hepatic fibrosis. 2014 · цитирований: 86
A systematic review of data on biological variation for alanine aminotransferase, aspartate aminotransferase and γ-glutamyl transferase. 2013 · цитирований: 62
The effects of beta-alanine supplementation on performance: a systematic review of the literature. 2014 · цитирований: 47
Occurrence of β-N-methylamino-l-alanine (BMAA) and Isomers in Aquatic Environments and Aquatic Food Sources for Humans. 2018 · цитирований: 38
Complex association between alanine aminotransferase activity and mortality in general population: a systematic review and meta-analysis of prospective studies. 2014 · цитирований: 38
A Systematic Risk Assessment and Meta-Analysis on the Use of Oral β-Alanine Supplementation. 2019 · цитирований: 33
Histologic changes in liver tissue from patients with chronic hepatitis B and minimal increases in levels of alanine aminotransferase: a meta-analysis and systematic review. 2014 · цитирований: 29
Elevated alanine aminotransferase is strongly associated with incident metabolic syndrome: a meta-analysis of prospective studies. 2013 · цитирований: 28
A systematic review of analytical methods for the detection and quantification of β-N-methylamino-l-alanine (BMAA). 2019 · цитирований: 26
Effect of Carnosine or β-Alanine Supplementation on Markers of Glycemic Control and Insulin Resistance in Humans and Animals: A Systematic Review and Meta-analysis. 2021 · цитирований: 25
The Muscle Carnosine Response to Beta-Alanine Supplementation: A Systematic Review With Bayesian Individual and Aggregate Data E-Max Model and Meta-Analysis. 2020 · цитирований: 21
Effect of therapeutic doses of acetaminophen (up to 4 g/day) on serum alanine aminotransferase levels in subjects consuming ethanol: systematic review and meta-analysis of randomized controlled trials. 2012 · цитирований: 19
Effects of Beta-Alanine Supplementation on Physical Performance in Aerobic-Anaerobic Transition Zones: A Systematic Review and Meta-Analysis. 2020 · цитирований: 16
Systematic review with meta-analysis: Significant histological changes among treatment-naïve chronic hepatitis B patients with normal alanine aminotransferase levels by different criteria. 2023 · цитирований: 15
Loss of alanine-glyoxylate and serine-pyruvate aminotransferase expression accelerated the progression of hepatocellular carcinoma and predicted poor prognosis. 2019 · цитирований: 15
Effects of beta-alanine supplementation on performance and muscle fatigue in athletes and non-athletes of different sports: a systematic review. 2017 · цитирований: 14
Prognostic Role of Pretreatment De Ritis Ratio (Aspartate Transaminase/Alanine Transaminase Ratio) in Urological Cancers: A Systematic Review and Meta-Analysis. 2020 · цитирований: 12
β-Alanine Supplementation in Combat Sports: Evaluation of Sports Performance, Perception, and Anthropometric Parameters and Biochemical Markers-A Systematic Review of Clinical Trials. 2023 · цитирований: 11
Effects of beta-alanine supplementation on body composition: a GRADE-assessed systematic review and meta-analysis. 2022 · цитирований: 11
Effect of β-alanine and sodium bicarbonate co-supplementation on the body's buffering capacity and sports performance: A systematic review. 2023 · цитирований: 11
Individual Participant Data Meta-Analysis Provides No Evidence of Intervention Response Variation in Individuals Supplementing With Beta-Alanine. 2021 · цитирований: 10
Effects of beta-alanine supplementation on Yo-Yo test performance: A meta-analysis. 2021 · цитирований: 6
Dosing strategies for β-alanine supplementation in strength and power performance: a systematic review. 2025 · цитирований: 5
Effects of Creatine and β-Alanine Co-Supplementation on Exercise Performance and Body Composition: A Systematic Review. 2025 · цитирований: 5
Оценка: Brain 25 Evidence (MIT).