Сосуды
Чеснок
Работает. Доказано: АД −2-4 мм рт.ст., липиды чуть: умеренно, САД −3.7, ДАД −2.0 мм рт.ст..
Суть
Серосодержащие соединения: умеренный эффект на АД и холестерин.
Что говорят исследования
Форма важна
Стандартизация 1.3% аллицина.
Aged garlic extract (AGE) лучше переносится..
Мифы
«Заменит статины»: эффект скромный.
«Свежий чеснок равноценен»: добавки стабильнее.
Осторожно
Чеснок (Allium sativum).
Для давления: мета-анализы показывают умеренное снижение (-5-8 мм рт.ст. систолическое).
Для холестерина: умеренное снижение.
Для кардиометаболических факторов: есть данные.
Эффект зависит от формы (aged garlic extract лучше).
Безопасен в стандартных дозах.
Осторожно: антикоагулянты, операции (антиагрегантный эффект).
С лекарствами
Из еды
Свежий чеснок (2-4 зубчика/сут); добавки = экстракт аллицина.
Источники
The Effect of Aged Garlic Supplementation on Blood Pressure and Lipid Profile: A Dose-Response Grade-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials. 2025 Journal Article, Systematic Review, Meta-Analysis
Systematic review and meta-analysis of randomised, controlled trials on the effects of garlic supplementation on serum adiponectin and leptin levels. 2021 Meta-Analysis, Systematic Review, Journal Article
Effects of Garlic Supplementation on Cardiovascular Risk Factors in Adults: A Comprehensive Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials. 2026 Journal Article, Systematic Review, Meta-Analysis
Обзоры исследований: 74 в Europe PMC, самые цитируемые
Effect of garlic on total serum cholesterol. A meta-analysis. 1993 · цитирований: 164
Garlic for treating hypercholesterolemia. A meta-analysis of randomized clinical trials. 2000 · цитирований: 156
A meta-analysis of the effect of garlic on blood pressure. 1994 · цитирований: 120
Garlic consumption and cancer prevention: meta-analyses of colorectal and stomach cancers. 2000 · цитирований: 118
Effect of garlic on blood pressure: a systematic review and meta-analysis. 2008 · цитирований: 106
Garlic as a lipid lowering agent--a meta-analysis. 1994 · цитирований: 102
Effect of garlic on serum lipids: an updated meta-analysis. 2013 · цитирований: 97
Garlic Lowers Blood Pressure in Hypertensive Individuals, Regulates Serum Cholesterol, and Stimulates Immunity: An Updated Meta-analysis and Review. 2016 · цитирований: 96
Anticancer potential of garlic and its bioactive constituents: A systematic and comprehensive review. 2021 · цитирований: 90
Effects of garlic on blood pressure in patients with and without systolic hypertension: a meta-analysis. 2008 · цитирований: 72
The impact of garlic on lipid parameters: a systematic review and meta-analysis. 2009 · цитирований: 57
Does garlic reduce risk of colorectal cancer? A systematic review. 2007 · цитирований: 53
Garlic for hypertension: A systematic review and meta-analysis of randomized controlled trials. 2015 · цитирований: 52
Effect of garlic on blood pressure: a meta-analysis. 2015 · цитирований: 46
The effect of garlic on lipid profile and glucose parameters in diabetic patients: A systematic review and meta-analysis. 2019 · цитирований: 44
Garlic for the common cold. 2014 · цитирований: 44
An umbrella review of garlic intake and risk of cardiovascular disease. 2016 · цитирований: 43
Allium vegetables and garlic supplements do not reduce risk of colorectal cancer, based on meta-analysis of prospective studies. 2014 · цитирований: 41
Anti-hyperlipidemia of garlic by reducing the level of total cholesterol and low-density lipoprotein: A meta-analysis. 2018 · цитирований: 40
Garlic supplementation and serum cholesterol: a meta-analysis. 2009 · цитирований: 38
Garlic for the prevention of cardiovascular morbidity and mortality in hypertensive patients. 2012 · цитирований: 37
Effect of garlic on plasma lipoprotein(a) concentrations: A systematic review and meta-analysis of randomized controlled clinical trials. 2016 · цитирований: 36
Garlic: A systematic review of the effects on cardiovascular diseases. 2023 · цитирований: 35
A systematic review and metaanalysis on the effects of garlic preparations on blood pressure in individuals with hypertension. 2015 · цитирований: 35
A meta-analysis of randomized, double-blind, placebo-controlled trials for the effects of garlic on serum lipid profiles. 2012 · цитирований: 35
Meta-analysis: Does garlic intake reduce risk of gastric cancer? 2015 · цитирований: 31
The roles of garlic on the lipid parameters: a systematic review of the literature. 2013 · цитирований: 29
Garlic Supplementation Reduces Circulating C-reactive Protein, Tumor Necrosis Factor, and Interleukin-6 in Adults: A Systematic Review and Meta-analysis of Randomized Controlled Trials. 2019 · цитирований: 25
Garlic consumption and colorectal cancer risk in man: a systematic review and meta-analysis. 2016 · цитирований: 25
The effects of garlic supplementation on oxidative stress markers: A systematic review and meta-analysis of randomized controlled trials. 2020 · цитирований: 24
Оценка: Brain 25 Evidence (MIT).